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Leukoplakia: A Premalignant or Precancerous Lesion Although leukoplakia is not associated with a specific histopathologic diagnosis, it is considered to be a premalignant lesion for the risk of malignant transformation is greater in a leukoplakic lesion than that associated with normal or unaltered mucosa. Image: Caption: Figure 1: A characteristic well-defined white patch of homogeneous leukoplakia on the left commissure in this bidi smoker.Note the pigmented areas (arrow) commonly observed in habitual smokers, posterior to the leukoplakia. Figure 2: Homogeneous leukoplakia on the left buccal mucosa with central fissuring and pigmented areas-common in bidi smokers; note the mucocoele (arrow) at Differential diagnosis Lichen planus, cinnamon contact stomatitis, candidiasis, hairy leukoplakia, lichen planus reactions, chronic biting, tobacco pouch keratosis, leukoedema, chemical burn, uremic stomatitis,skin graft, some genodermatoses and discoid lupus erythematosus. Conclusions: The differential diagnosis of oral lichen planus - particularly its reticular form - and homogenous leukoplakia should be based on anamnesis, physical examination and histological Leukoplakia can be either solitary or multiple.

Phase 1) therapy (scaling) was performed. 2). 2018-05-22 0.6% and 5% of homogenous leukoplakia and between 20-25% of non-homogenous leukoplakia unpredictably undergo malignant transformation (2, 7) and it is estimated that between 17% and 35% of oral SCC arise from pre-existing oral leukoplakia. The remaining oral SCC arise de novo from apparently normal oral epithelium (6).

Oral candidiasis: Oral hairy leukoplakia is often colonised by candida which can obfuscate the pathology. Human papillomavirus (HPV): The koilocyte-like cells in oral hairy leukoplakia resemble HPV infection.

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Leukoplakia Differential Diagnosis. The differential diagnosis of this disorder involves distinguishing it from other conditions that produce similar symptoms. These include, Hyperkeratosis; Dysplasia; Squamous carcinoma; Lichen planus; Candidosis; Lupus erythematosis Homogeneous leukoplakia is defined as a predominantly white lesion of uniform flat and thin appearance that may exhibit shallow cracks and that has a smooth, wrinkled or corrugated surface with a consistent texture throughout.

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Differential diagnosis of homogenous leukoplakia

Verrucous leukoplakia6. Proliferative Verrucous leukoplakia(PVL)7. Erythroleukoplakia Clinical Types continued, Histopathology & Malignant potential Differential Diagnosis & Management of leukoplakia References: Shafer’sTextbook Of Oral Pathology; Random google images Leukoplakia Differential Diagnosis.

Oral hairy leukoplakia shows a gently papillated surface, a prominent horny layer with confluent bacterial overgrowth, and ballooned epithelial cells with a distinct perinuclear halo in a bandlike arrangement. working on differential diagnosis. On the basis of clinical history a . provisional diagnosis of Homogenous Leukoplakia was made.
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Tumors Retinoblastoma Medulloepithelioma Leukemia Combined retinal hamartoma Astrocytic hamartoma (Bourneville’s tuberous sclerosis) 2. Congenital malformations Persistent fetal vasculature (PFV) Posterior coloboma Retinal fold Myelinated nerve fibers The differential diagnosis should include idiopathic leukoplakia, smoker's keratosis, frictional keratosis, hyperplastic candidiasis, lichen planus, lichenoid reaction etc.

11 Mar 2020 White plaques of questionable risk, diagnosed when other known diseases or Multiple clinical forms exist: homogeneous, speckled, nodular, and verrucous. homogeneous white plaques; other causes for white lesions&nbs 26 Oct 2016 Leukoplakia is the term used for a white lesion that is precancerous and and dyskeratosis congenita causes leukoplakias and oral cancer at a Clinically, leukoplakias are divided into homogenous and nonhomogeneous&n Histopathology of leukoplakia can disclose hyperkeratosis with dysplasia or carcinoma or dyskeratosis congenita causes leukoplakias and oral cancer at a young homogeneous type is usually a thin, flat, and uniform white plaque with 25 Jul 2016 The clinical differential diagnosis for PVL would include frictional keratosis, homogenous leukoplakia, squamous papilloma, verrucous Based on clinical examinations a provisional diagnosis of leukoplakia is made when Homogeneous leukoplakia is defined as a predominantly white lesion of Differential diagnosis includes lichen planus, lupus, leukoedema, candidosis, Oral leukoplakia lesions were the most prevalent (0.65%) and oral erythroplakia Sometimes these lesions are also attributed to idiopathic causes(,). lateral surface of the tongue), and non-homogeneous lesions with exophytic, papil 6 Feb 2018 highlights the fact that the diagnosis of leukoplakia is one of exclusion [1]. or indistinct and smoothly countered or ragged, homogenous or rough in believe that it satisfies hunger, causes euphoria and makes breat out, a patient is diagnosed with oral leukoplakia.
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Case report on oral leukoplakia with superadded fungal infection Mahalaxmi L. Lature, Krishna Burde Departments of Oral Medicine and Radiology, SDM College of Dental Sciences and Hospital, Dharwad, Karnataka, India Abstract Leukoplakia of the oral cavity is a precancerous lesion has a malignant potential and life threatening if not diagnosed early. Introduction: Leukoplakia (LKP) is defined as a white patch or plaque on the mucosa of oral cavity, vulva, vagina etc., which cannot be removed and cannot be clinically or microscopically explained by presence of a disease. LKP is included in the group of lesions with malignant potential. Microscopic characteristics: Basic microscopic characteristics of oral LKP include hyperkeratosis of ortho- or parakeratotic type and acanthosis of the epithelium, with various degrees of Differential diagnosis of oral hairy leukoplakia. Oral candidiasis: Oral hairy leukoplakia is often colonised by candida which can obfuscate the pathology.

If the lesion can be removed, it may represent a pseudomembrane, a fungus colony, or debris. Leukoplakia is a discomforting condition that affects around 3% of the world population. Read and know what is Leukoplakia as well as all about its causes, symptoms, diagnosis, treatment and prevention.